Endocrine Abstracts

Objectives: The study of the real indications for thyroid ultrasound and in which pathological conditions the echography is of real use and not for abuse.Material and methods: In the last 10 years, over 13 000 echographies were performed in 5136 consecutive patients for ‘thyroid disturbances’. In a previous paper we described 7 echographic patterns for thyroid ultrasound (9th ECE). The diagnosis of Hashimoto’s thyroiditis (HT) was consider...

Introduction: The prevalence of autoimmune disorders (AID) is more frequent in patients with Hashimoto’s thyroiditis (HT).Aim: To see if the clinical and biochemical aspects are different among the patients with HT and if they change related to the systemic or organ specific AID.Material and method: A. HT was diagnosed on antithyroperoxidase antibodies (ATPO) over 34 UI/ml. B. 491 patients with HT were investigat...

Objectives: To analyze the conceptual frame for a correlation between thyroid echographic description and antithyroid peroxydase antibodies (ATPO) levels in Hashimoto’s thyroiditis (HT).Material-methods: A. 783 patients: 396 with HT (ATPO>34 UI/ml), 386-control (ATPO<34 UI/ml). B. Ultrasound aspects were described in 8 patterns: 0-thyroid lack; 1 – hypoechogenic and pseudonodular; 2 – hypoechogenic and homogenous; 3 &...

Introduction: Teriparatide is prescribed for severe osteoporosis based on national protocols. The osteoanabolic drug is followed by an anti-resorbtive medication.Aim: We analyze the treatment sequence options after Teriparatide in patients who finished the 2-year protocol or were early droppers.Material and method: This is a real life study based on Romanian protocol of Teriparatide for severe primary or/and glucocorticoid osteopor...

Introduction: VD deficiency is associated with the atrophy of muscle fibres (predominantly type II). This leads to decreased muscle force and general physical performance.Objective: To analyse the relationship between the serum concentration of 25-hydroxy vitamin D (25OHD), balance and physical performance in women with VD deficiency and the effect of VD supplementation or treatment with a VD analog.Materials and methods: We analys...

Background: Low serum sodium levels were associated both in experimental studies and in clinical practice with increased prevalence of osteoporosis, due to decreased bone mineralization and increased osteoclastic activity. On the other hand, hyponatremia – independent of osteoporosis – is associated with fracture occurrence.Objectives: To assess the relationship between serum sodium levels and osteoporotic fractures.Patie...

Background: Hypothyroidism is a frequent side effect of external radiotherapy of the cervical region for head and neck cancer. Up to 33% of irradiated patients developed primary hypothyroidism within 2 years after radiation therapy. The risk of hypothyroidism increases with radiation dose.Patients and methods: Four patients (2M/2F), aged 53.3±13.9 years, resident both in iodine sufficient (n=2) and iodine deficient areas (n=2), wer...

Aim/objectives: To investigate relationships between thyroid function, antithyroperoxydase antibodies (ATPO), antithyroglobuline antibodies (ATG) and correlations with echographic pattern in Hashimoto thyroiditis and related diseases.Materials and methods: Diagnosis: i) ATPO >34 μ/ml=Hashimoto thyroiditis (HT); ii) ATPO=normal with high ATG=thyroiditis with only hyper-ATG (T-ATG). Thyroid function: TSH. Echographic patterns=10 (Peretianu, this C...

Study: Retrospective, cohort.Material and methods: A. Hashimoto thyroiditis (HT) diagnosis: i) antithyroperoxydase antibodies (ATPO) criteria; cut-off >34 IU/ml. ii) If ATPO=normal (N), HT was considered only antithyroglobuline antibodies (ATG) were >50 IU/ml (↑) and ultrasound was pattern 1 (pseudonodular, intense hypoechogenic, inhomogeneous – Peretianu, Endocrine Abstracts, 2007, 14, P340; 2008, 16, P772; 2009, 20, P79).<p class...

Premises: Numerous recent medical journals and communications insist on the high prevalence of Hashimoto’s thyroiditis (HT) associated with breast cancer in women (see www.ncbi.nlm.nih.gov/ key words: breast cancer, thyroiditis, #91).Objective: We proposed to present data from our casuistry related to HT (over 2000 patients and control, including men), observed during last 10 years.Mat...